Although Cissampelos capensis is usually a shrub, it may sprawl over rocks or twine into adjacent shrubbery. The many stems (with no tendrils) tend to become a tangled mass or reach for more around it. The sought-after root, much used in traditional medicine, becomes 2,5 cm in diameter. It is covered in grey-brown bark. The plant may be confused with Zehneria scabra, a plant from the Cucurbitaceae or cucumber family, also sharing the dawidjieswortel common name with C. capensis; but that plant grows spirally coiled tendrils.
The species distribution ranges from Namibia through the Northern Cape and the Western Cape to the Eastern Cape as far as Gqeberha (Port Elizabeth).
The habitat is diverse scrub, succulent Karoo and Nama Karoo. The habitat population is deemed of least concern early in the twenty first century.
C. capensis has a very diverse and extended set of medicinal applications, including treatment for snakebite, boils, dysentery, kidney stones, spastic colon, some cancers, cholera, diabetes, glandular swellings, syphilis and blood purification. If one adds the purported value as a painkiller, a sedative, a purgative and an improver of memory, its incredible fame as a panacea might well have started at the time when King David is said to have discovered where to dig for it as a shepherd.
Expertise regarding the precise method(s) of correct usage for each ailment is important because plants of this family, maybe even this one, are included on the list of providers of arrow poison. When such a list of benefits becomes inordinately long, doubt should result in seeking corroborative evidence; especially when discovering that pieces of the root used to be worn as protective charms attached to various body parts (Vlok and Schutte-Vlok, 2015; Van Wyk and Gericke, 2000; Van Wyk, et al, 1997; iNaturalist; https://pza.sanbi.org; http://redlist.sanbi.org).